Opponent: Duke
| H/A/N | Games | Wins | Losses | % |
| All Games | 12 | 3 | 9 | .250 |
| Home | 1 | 0 | 1 | .000 |
| Away | 9 | 2 | 7 | .222 |
| Neutral | 2 | 1 | 1 | .500 |
HomeAwayNeutral
Displaying 1-12 of 12 results.
| Season | Date | Rank | Opponent | Opp. Rank | Site | H/A | Innings | WVU | Opp | W/L | Attendance |
| 2022 | March 15, 2022 | | Duke | | Durham Bulls Athletic Park | A | 9 | 1 | 2 | L | 371 |
| 2019 | June 1, 2019 | 15 | Duke | | Monongalia County Ballpark | H | 9 | 0 | 4 | L | 4,258 |
| 2014 | February 28, 2014 | | Duke | | TicketReturn.com Field | N | 9 | 3 | 1 | W | 475 |
| 1995 | February 26, 1995 | | Duke | | Jack Coombs Field | A | 9 | 3 | 13 | L | 650 |
| 1995 | February 25, 1995 | | Duke | | Jack Coombs Field | A | 9 | 8 | 14 | L | 575 |
| 1994 | February 27, 1994 | | Duke | | Jack Coombs Field | A | 9 | 3 | 4 | L | 100 |
| 1994 | February 26, 1994 | | Duke | | Jack Coombs Field | A | 9 | 3 | 1 | W | 150 |
| 1994 | February 25, 1994 | | Duke | | Jack Coombs Field | A | 9 | 12 | 8 | W | 200 |
| 1961 | June 3, 1961 | | Duke | 17 | Sims Legion Park | N | 9 | 3 | 7 | L | 525 |
| 1950 | April 6, 1950 | | Duke | | Duke Park | A | 9 | 5 | 9 | L | 100 |
| 1950 | April 5, 1950 | | Duke | | Duke Park | A | 9 | 3 | 9 | L | 100 |
| 1930 | April 21, 1930 | | Duke | | Hanes Field | A | 9 | 11 | 22 | L | 100 |
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