| Date | Opponent | Score | W/L | Att. |
| Tue Nov 9 | Oakland | 60-53 | W | 9,408 |
| Fri Nov 12 | Pitt | 74-59 | W | 14,100 |
| Thu Nov 18 | vs Elon | 87-68 | W | 4,213 |
| Fri Nov 19 | vs Marquette | 71-82 | L | 4,672 |
| Sun Nov 21 | vs Clemson | 66-59 | W | 4,820 |
| Fri Nov 26 | Eastern Kentucky | 80-77 | W | 10,062 |
| Tue Nov 30 | Bellarmine | 74-55 | W | 9,523 |
| Sat Dec 4 | Radford | 67-51 | W | 11,014 |
| Wed Dec 8 | Connecticut (15) | 56-53 | W | 12,045 |
| Sun Dec 12 | Kent State | 63-50 | W | 11,532 |
| Sat Dec 18 | vs UAB | 65-59 | W | 8,427 |
| Wed Dec 22 | Youngstown State | 82-52 | W | 9,784 |
| Sat Jan 1 | @ Texas (17) * | 59-74 | L | 12,864 |
| Sat Jan 8 | Kansas State * | 71-68 | W | 11,919 |
| Tue Jan 11 | Oklahoma State * | 70-60 | W | 10,352 |
| Sat Jan 15 | @ Kansas (9) * | 59-85 | L | 16,300 |
| Tue Jan 18 | Baylor (5) * | 68-77 | L | 12,692 |
| Sat Jan 22 | @ Texas Tech (18) * | 65-78 | L | 14,556 |
| Wed Jan 26 | Oklahoma * | 62-72 | L | 10,997 |
| Sat Jan 29 | @ Arkansas | 68-77 | L | 19,200 |
| Mon Jan 31 | @ Baylor (8) * | 77-81 | L | 8,226 |
| Sat Feb 5 | Texas Tech (14) * | 53-60 | L | 12,673 |
| Tue Feb 8 | Iowa State * | 79-63 | W | 11,191 |
| Sat Feb 12 | @ Oklahoma State * | 58-81 | L | 8,013 |
| Mon Feb 14 | @ Kansas State * | 73-78 | L | 5,401 |
| Sat Feb 19 | Kansas (6) * | 58-71 | L | 14,012 |
| Mon Feb 21 | @ TCU * | 67-77 | L | 5,374 |
| Wed Feb 23 | @ Iowa State * | 81-84 | L | 12,810 |
| Sat Feb 26 | Texas (20) * | 81-82 | L | 13,470 |
| Tue Mar 1 | @ Oklahoma * | 59-72 | L | 7,259 |
| Sat Mar 5 | TCU * | 70-64 | W | 11,324 |
| Wed Mar 9 | vs Kansas State | 73-67 | W | 15,295 |
| Thu Mar 10 | vs Kansas (6) | 63-87 | L | 15,845 |
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