| Date | Opponent | Score | W/L | Att. |
| Fri Nov 9 | Buffalo | 94-99 | L | 12,657 |
| Thu Nov 15 | vs Monmouth | 71-53 | W | 3,307 |
| Fri Nov 16 | vs Western Kentucky | 57-63 | L | 3,370 |
| Sun Nov 18 | vs Saint Joseph's | 97-90 | W | 3,094 |
| Sat Nov 24 | Valparaiso | 88-76 | W | 9,188 |
| Wed Nov 28 | Rider | 92-78 | W | 9,124 |
| Sat Dec 1 | Youngstown State | 106-72 | W | 10,849 |
| Tue Dec 4 | vs Florida | 56-66 | L | 8,499 |
| Sat Dec 8 | Pitt | 69-59 | W | 13,670 |
| Sun Dec 16 | vs Rhode Island | 70-83 | L | 5,812 |
| Sat Dec 22 | Jacksonville State | 74-72 | W | 8,231 |
| Sun Dec 30 | Lehigh | 78-68 | W | 10,754 |
| Wed Jan 2 | Texas Tech (11) * | 59-62 | L | 10,358 |
| Sat Jan 5 | @ Texas * | 54-61 | L | 9,195 |
| Wed Jan 9 | @ Kansas State * | 69-71 | L | 9,590 |
| Sat Jan 12 | Oklahoma State * | 77-85 | L | 11,339 |
| Tue Jan 15 | @ TCU * | 67-98 | L | 6,734 |
| Sat Jan 19 | Kansas (7) * | 65-64 | W | 12,657 |
| Mon Jan 21 | Baylor * | 73-85 | L | 9,936 |
| Sat Jan 26 | @ Tennessee (1) | 66-83 | L | 22,149 |
| Wed Jan 30 | @ Iowa State (20) * | 68-93 | L | 14,252 |
| Sat Feb 2 | Oklahoma * | 79-71 | W | 11,611 |
| Mon Feb 4 | @ Texas Tech (18) * | 50-81 | L | 12,831 |
| Sat Feb 9 | Texas * | 53-75 | L | 12,815 |
| Sat Feb 16 | @ Kansas (14) * | 53-78 | L | 16,300 |
| Mon Feb 18 | Kansas State (23) * | 51-65 | L | 9,266 |
| Sat Feb 23 | @ Baylor * | 75-82 | L | 6,262 |
| Tue Feb 26 | TCU * | 104-96 | W | 8,798 |
| Sat Mar 2 | @ Oklahoma * | 80-92 | L | 7,921 |
| Wed Mar 6 | Iowa State * | 90-75 | W | 10,354 |
| Sat Mar 9 | @ Oklahoma State * | 77-85 | L | 7,279 |
| Wed Mar 13 | vs Oklahoma | 72-71 | W | 18,858 |
| Thu Mar 14 | vs Texas Tech (7) | 79-74 | W | 18,927 |
| Fri Mar 15 | vs Kansas (17) | 74-88 | L | 19,066 |
| Wed Mar 20 | Grand Canyon | 77-63 | W | 5,313 |
| Mon Mar 25 | Coastal Carolina | 91-109 | L | 6,775 |
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